LA Dodgers at Cleveland 1:10 PM ET
A team can never have too much starting pitching.
San Francisco at Detroit 1:10 PM ET
San Francisco Giants right-hander Landen Roupp, who hasn't allowed a run in his past two starts, will look to extend that streak during a Wednesday matinee against the host Detroit Tigers.
Chi. White Sox at NY Mets 1:10 PM ET
Getting off to fast starts hasn't been a problem lately for the otherwise offensively challenged New York Mets.
Minnesota at Tampa Bay 1:10 PM ET
Tampa Bay Rays right-hander Drew Rasmussen appears to be getting comfortable with longer starts as he works his way back following his third major elbow surgery.
Athletics at Houston 2:10 PM ET
The Houston Astros remain coy regarding the availability of slugger Yordan Alvarez, who resides on the 15-day injured list and missed his 23rd consecutive game Tuesday.
Pittsburgh at Arizona 3:40 PM ET
Miami at San Diego 4:10 PM ET
Whoever said you never get a second chance to make a first impression hasn't heard of Kyle Hart.
St. Louis at Baltimore 6:35 PM ET
The St. Louis Cardinals might be feeling comfortable in close games because they've played quite a few.
Cincinnati at Kansas City 7:40 PM ET
Cincinnati's Hunter Greene has established himself as one of the best young pitchers in the majors.
Colorado at Chi. Cubs 8:05 PM ET
The Chicago Cubs boast the majors' highest-scoring offense, but their pitching staff has done the heavy lifting of late.
Toronto at Texas 8:05 PM ET
The Texas Rangers expect to receive a jolt to their lineup when they clash with the Toronto Blue Jays on Wednesday in the finale of a three-game series in Arlington, Texas.
NY Yankees at LA Angels 9:38 PM ET
The Los Angeles Angels expect to have catcher Logan O'Hoppe back in the starting lineup for the series finale against the New York Yankees on Wednesday night in Anaheim, Calif.
Washington at Seattle 9:40 PM ET
The Seattle Mariners will play their 54th game of the season when they play host to the Washington Nationals on Wednesday night, putting them one-third of the way through their 2025 campaign.